Measles – Madagascar

WHO is supporting the Ministry of Public Health of Madagascar to respond to an unusually large measles outbreak.

Yellow fever – Nigeria

On 22 November 2018, the World Health Organization was informed of a cluster of suspected Yellow fever (YF) cases and deaths in Edo State, Nigeria.

Poliomyelitis – Democratic Republic of the Congo

As of October 2018, genetically-linked circulating vaccine-derived poliovirus type 2 (cVDPV2) isolates were detected in two cases from Haut-Katanga province (Mufunga-Sampwe district) in the Democratic Republic of the Congo. The first case was a 11-year old child who experienced onset of acute flaccid paralysis (AFP) on 6 October. The second case was a 29-month old child who experienced onset of symptoms on 7 October, and is a known contact of the first case. The isolated viruses are a new emergence and unrelated to previously-detected cVDPV2s affecting the country. This is the fourth distinct outbreak of cVDPV2 detected in the country since June 2017. In total, 42 cVDPV2 cases have now been confirmed since detection of the first outbreak in June 2017, 20 cases of which were detected in 2018.

In February 2018, the government declared cVDPV2 to be a national public health emergency. On 26 July 2018, the Minister of Health, WHO Director General, the Regional Director for Africa, and provincial governors convened an urgent, high-level meeting and signed the ‘Kinshasa Declaration for Polio Eradication’. Provincial governors pledged to provide the necessary oversight, accountability and resources required to urgently improve the quality of the outbreak response being implemented across the country. It is imperative that the remaining operational gaps in outbreak response are urgently filled with the appropriate oversight and engagement.

Hantavirus disease – Republic of Panama

The Panama Ministry of Health has reported an increase in cases of hantavirus infection in Los Santos Province, Republic of Panama, to the Pan American Health Organization / World Health Organization (PAHO/WHO). Between 1 January and 22 December 2018, a total of 103 confirmed cases of hantavirus have been reported at the national level, 99 of which were reported in Los Santos Province. In Los Santos Province, 51 cases were classified as hantavirus fever1 (HF) without pulmonary syndrome and 48 cases were classified as hantavirus pulmonary syndrome2 (HPS), including four deaths.

Cases were confirmed by serology and polymerase chain reaction (PCR)3. Sequencing determined that the type of virus associated with this outbreak is Choclo virus. It was first isolated in 1999 in the western Republic of Panama.

Middle East respiratory syndrome coronavirus (MERS-CoV) – Saudi Arabia

From 31 October through 30 November 2018, the International Health Regulations (IHR 2005) National Focal Point of Saudi Arabia reported eight additional cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection, including two deaths. Details of these cases can be found in a separate document (see link below).

From 2012 through 30 November 2018, the total number of laboratory-confirmed MERS-CoV cases reported globally to WHO under IHR (2005) is 2274 with 806 associated deaths. The total number of deaths includes the deaths that WHO is aware of to date through follow-up with affected member states.